GLP-1 research peptides: Retatrutide, Tirzepatide and Semaglutide
GLP-1 peptides are synthetic analogues built on the incretin hormones GLP-1 and GIP. We stock three, and they differ in how many receptors one chain binds. Semaglutide binds the GLP-1 receptor. Tirzepatide binds the GIP and GLP-1 receptors. Retatrutide binds the GIP, GLP-1 and glucagon receptors, which is why it is called a triple agonist.
All three carry a fatty diacid on a lysine side chain and non-coded amino acids such as Aib in the chain. Our table gives each one's length, formula, molar mass, CAS number and receptor targets next to the pack: Retatrutide 40mg and Tirzepatide 60mg in 3 ml pens, Semaglutide 10mg as lyophilised powder.
| Compound | Code | Amino acids | Receptor targets | Formula | Molar mass | CAS | Pack |
|---|---|---|---|---|---|---|---|
| Retatrutide | LY3437943 | 39 | GIP, GLP-1, glucagon | C221H342N46O68 | about 4,731 g/mol | 2381089-83-2 | 40mg in a 3 ml pen |
| Tirzepatide | LY3298176 | 39 | GIP, GLP-1 | C225H348N48O68 | about 4,813 g/mol | 2023788-19-2 | 60mg in a 3 ml pen |
| Semaglutide | NN9535 | 31 | GLP-1 | C187H291N45O59 | about 4,114 g/mol | 910463-68-2 | 10mg lyophilised powder |
Cagrilintide, an amylin analogue studied alongside Semaglutide, is listed here too.
Retatrutide has a published Janoshik report.
Compare them in Retatrutide vs Tirzepatide vs Semaglutide. Free tracked UK delivery, card payment and dispatch within 1 working day.
| Product | Pack | mg per ml | Price | Price per mg |
|---|---|---|---|---|
| RETATRUTIDE | 40MG / 3ML | 13.3 | £128.00 | £3.20/mg |
| Tirzepatide | 60MG / 3ML | 20 | £128.00 | £2.13/mg |
| Semaglutide | 10MG | £100.00 | £10.00/mg | |
| Cagrilintide | 10MG | £120.00 | £12.00/mg |
Questions
What are GLP-1 peptides?
GLP-1 peptides are synthetic analogues built on the incretin hormones GLP-1 and GIP.
What do single, dual and triple agonists mean?
They differ in how many receptors one chain binds. Semaglutide binds the GLP-1 receptor. Tirzepatide binds the GIP and GLP-1 receptors. Retatrutide binds the GIP, GLP-1 and glucagon receptors, which is why it is called a triple agonist.
Which of them come as pens?
Retatrutide 40mg and Tirzepatide 60mg come in 3 ml pens. Semaglutide 10mg is supplied as lyophilised powder.
How should they be stored?
Store the pens at 2–8°C and refrigerate them on arrival. Store the Semaglutide powder at 2–8°C, sealed and away from light.